Clinical trial · Interventional
Inflammatory Response in Laparoscopic and Open Colectomy
Contribution to the Study of Inflammatory Response in Laparoscopic vs Open Colon Cancer Surgery
NCT00942461CI-TRIAL-00002480completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is designed to measure and compare the inflammatory response in laparoscopic and open colon cancer surgery
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic colectomy | Procedure | — | UNRESOLVED |
| Open colectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Laparoscopic Surgery group
- description
- Group of patients that are operated with laparoscopic approach
- interventionNames
- Procedure: Laparoscopic colectomy
- type
- ACTIVE_COMPARATOR
- label
- Open surgery Group
- description
- Group of patients operated with open approach
- interventionNames
- Procedure: Open colectomy
Primary outcomes (1)
- measure
- Inflammatory reaction of the patients organism in laparoscopic vs open colorectal surgery for cancer
- timeFrame
- preoperative, intraoperative, 6h postop, 24h postop
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * colorectal cancer Exclusion Criteria: * metastases * stage 4 colorectal cancer * recurrent disease * chronic diseases * obvious inflammatory condition
References
Publications (2)
- DERIVEDTsimogiannis KE, Tellis CC, Tselepis AD, Pappas-Gogos GK, Tsimoyiannis EC, Basdanis G. Toll-like receptors in the inflammatory response during open and laparoscopic colectomy for colorectal cancer. Surg Endosc. 2012 Feb;26(2):330-6. doi: 10.1007/s00464-011-1871-2. Epub 2011 Sep 5. PMID 21898023
- DERIVEDTsimogiannis KE, Telis K, Tselepis A, Pappas-Gogos GK, Tsimoyiannis EC, Basdanis G. Alpha-defensin expression of inflammatory response in open and laparoscopic colectomy for colorectal cancer. World J Surg. 2011 Aug;35(8):1911-7. doi: 10.1007/s00268-011-1140-5. PMID 21567262