Clinical trial · Observational
Freehand Ultrasound Elasticity Imaging in Liver Surgery
Application of Novel, High Resolution, and Freehand Ultrasound Elasticity Imaging in Liver Surgery
NCT00942383CI-TRIAL-00037833IOUSterminatedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): low accrual
Summary
Brief summary (as posted)
The purpose of this study is to investigate the potential for visualizing radiofrequency-induced (RFA) and microwave-induced (MWA) hepatic thermal ablation lesions using a novel, high resolution, and freehand ultrasound elasticity imaging method in human subjects.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Liver Tumors | Liver Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- IOUS-USEI
- description
- Receive intraoperative ultrasound (IOUS) using the Siemens Anteras to acquire ultrasound elasticity imaging (USEI) during standard of care surgical radiofrequency ablation and microwave ablation
Primary outcomes (1)
- measure
- Comparison of transverse ablation diameter between intraoperative ultrasound elasticity imaging (USEI) and postoperative cross-sectional imaging (CT or MRI).
- timeFrame
- 2 years
Secondary outcomes (4)
- measure
- Comparison of ablation volume between ultrasound elasticity imaging (USEI) and CT/MRI.
- timeFrame
- 2 years
- measure
- Correlation between "in vivo" versus phantom tumor size to validate the development of guidance systems combined with appropriate visualization and planning software for ablative therapy.
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Any patient eligible for open, laparoscopic, or percutaneous hepatic RFA or MWA as their surgical treatment due to either primary tumors of the liver as well as liver metastases. * Participants must be able to have post-operative CT/MRI at Johns Hopkins as their standard care. Exclusion Criteria: * Patients under 18 years old. * Pregnant women.
References
Publications (0)
Data not yet available
No reference posted for this study.