Clinical trial · Interventional
Comparison of Mechanical Bowel Preparation Versus Enema for Candidates to Colorectal Resection for Adenocarcinoma
Effect of Mechanical Bowel Preparation With Polyethylene Glycol Plus Bowel Enema (Glycerine 5%) vs Bowel Enema Alone in Patients Candidates to Colorectal Resection for Malignancy. Prospective, Randomized Clinical Trial
NCT00940030CI-TRIAL-00035660MBPcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate mechanical bowel preparation (MBP) with polyethylene glycol plus bowel enema versus bowel enema alone in patients candidates to colorectal resection for malignancy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| enema | Other | — | UNRESOLVED |
| mechanical bowel preparation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- MBP+enema
- description
- mechanical bowel preparation and enema
- interventionNames
- Other: mechanical bowel preparation
- Other: enema
- type
- ACTIVE_COMPARATOR
- label
- enema
- interventionNames
- Other: enema
Primary outcomes (1)
- measure
- Anastomotic leakage, wound infection (including deep abscess)
- timeFrame
- 30 days after surgery
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients candidates to colorectal surgery for histologically confirmed colorectal cancer * Age 18-80 years * Obtained written consent Exclusion Criteria: * Patients at high risk for receiving a stoma (e. g. patients affected by distal rectal cancer \<5cm from the anal verge; patients whose tumour is located \>5 cm from the anal verge who underwent neoadjuvant CT-RT without downstaging or tumour shrinkage * Intestinal obstruction * Emergency procedures * Patients who underwent colonoscopy within 7 day from surgery * ASA 4-5 patients * Patients unable to give informed consent * Renal failure (serum creatinine \>3 mg/dl) * Pregnant women * Breast feeding women
References
Publications (0)
Data not yet available
No reference posted for this study.