Clinical trial · Interventional
Smoking Cessation Treatment for Head and Neck Cancer Patients
NCT00931021CI-TRIAL-00011359terminatedEarly Phase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a pilot research study examining the use of varenicline (Chantix) and the nicotine patch. The study is designed to find out whether one of these medications is more effective for smoking cessation with head and neck cancer patients. The study has three parts: 1) two intake sessions; 2) an 8-week treatment phase, and 3) a 3-month follow-up.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Smoking Cessation | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nicotine Patch | Drug | — | UNRESOLVED |
| Varenicline (Chantix) | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Varenicline (Chantix)
- interventionNames
- Drug: Varenicline (Chantix)
- type
- ACTIVE_COMPARATOR
- label
- Nicotine Patch
- interventionNames
- Drug: Nicotine Patch
Primary outcomes (1)
- measure
- To develop an effect size estimate for smoking cessation defined as continuous abstinence over the last 4 weeks of treatment for 2 mg varenicline compared to nicotine patch.
- timeFrame
- Eight weeks
Secondary outcomes (3)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * age 18 or older * smoking 10 or more cigarettes per day * diagnosed with and completed an initial course of treatment for any type of head and neck cancer * life expectancy of 12 months or more Exclusion Criteria: * history of allergic reactions to adhesives * unstable psychiatric/medical conditions such as suicidal ideation, acute psychosis, severe alcohol dependence, or dementia * females of childbearing potential who are pregnant, nursing, or not practicing effective contraception
References
Publications (0)
Data not yet available
No reference posted for this study.