Clinical trial · Interventional
Cryoablation Versus Radiofrequency Ablation for Small Renal Masses
A Prospective Randomized Pilot Trial of Cryoablation (CA) Versus Radio Frequency Ablation (RFA) for the Management of Small Renal Masses
NCT00922948CI-TRIAL-00023268withdrawnPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Cryoablation is no longer offered at our hospital, and likely won't be offered in the near future.
Summary
Brief summary (as posted)
The purpose of this study is to verify the oncological efficacy and safety of cryoablation and radiofrequency ablation for the treatment of small renal tumors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Cancers | Kidney Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cryoablation | Procedure | — | UNRESOLVED |
| Radiofrequency ablation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Cryoablation
- interventionNames
- Procedure: Cryoablation
- type
- ACTIVE_COMPARATOR
- label
- Radiofrequency ablation
- description
- Radiofrequency ablation
- interventionNames
- Procedure: Radiofrequency ablation
Primary outcomes (1)
- measure
- Treatment failure rate.
- timeFrame
- Baseline, Weeks 6, 12, 24, 36, 48
Secondary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with tumors that progress in size while on a watchful waiting protocol; * Patients with multiple tumors; * Patients with a tumor in a solitary kidney; * Patients with poor renal function and a renal tumor; * Patients with significant co-morbidities that may benefit from a less invasive approach. Exclusion Criteria: * Large tumors \> 4.0cm; * Unable to have a general anesthetic; * Unable to comply with follow-up protocol (i.e., routine CT or MRI and a follow-up biopsy); * Uncorrectable bleeding diathesis; * Evidence of metastatic disease.
References
Publications (0)
Data not yet available
No reference posted for this study.