Clinical trial · Observational
Micro-RNA (miR) Expression in Upper Gastrointestinal Mucosal Tissue
Micro-RNA (miR) Expression in Upper Gastrointestinal Mucosal Tissue: A Potential Target for Understanding and Preventing the Progression of Barrett's Esophagus
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a laboratory-based, exploratory study using tissue obtained from our clinical practice. The purpose of this study is to confirm our ability to characterize miR expression in various tissues (proximal and distal esophagus, stomach and duodenum) obtained from the upper gastrointestinal tract in preparation for the study of MiR in patients with Barrett's esophagus and other inflammatory conditions of the upper gastrointestinal tract.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Barrett's Esophagus | — | UNRESOLVED | — |
| Esophageal Adenocarcinoma | Esophageal Adenocarcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- No treatment
- description
- genetic research project; to meet inclusion criteria, participants must have normal upper GI tract upon upper endoscopy, for study biopsies to be taken
Primary outcomes (1)
- measure
- miR expression between tissue from Barrett's esophagus and that from normal tissues
- timeFrame
- time it takes to have standard of care biopsies taken during one routine Upper Endoscopy
Secondary outcomes (1)
- measure
- expression of miR in Barrett's esophagus patients with cancer in comparison to those who do not progress to cancer
- timeFrame
- time it takes to have standard of care biopsies during one routine Upper Endoscopy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * willingness to give consent * normal gross appearance of the esophagus, stomach and duodenum Exclusion Criteria: * contraindication to mucosal biopsy
References
Publications (0)
Data not yet available