A Study of a Live Intranasal Influenza Vaccine in Children With Cancer

Inclusion Criteria:

* Age 2 through 21 (not yet reached their 22nd birthday) at the time of entry into the study
* Participant or participants parent/legal guardian available by telephone during the course of the study;
* Written informed consent (and assent, if applicable) obtained
* Currently receiving chemotherapy and /or radiotherapy for the treatment of cancer or have received chemotherapy in the past 12 weeks;
* If the participant's underlying cancer is a solid tumor, current status must be stable disease, partial response, or complete response to therapy; if the participant's underlying disease is a hematological malignancy, current status must be in remission, and if receiving chemotherapy, must be in the "continuation" or "maintenance" phase of therapy or equivalent;
* Estimated life expectancy of \> 1 year

Exclusion Criteria:

* History of hypersensitivity to any component of FluMist or TIV, including egg or egg products, gelatin, or monosodium glutamate;
* History of hypersensitivity to gentamicin;
* Close contact with a severely immunocompromised patient (e.g., a hematopoietic stem cell transplant patient, during those periods in which the immunocompromised patient requires care in a protective environment
* History of Guillain-Barre´ syndrome;
* History of asthma;
* Female who is breastfeeding or lactating;