Clinical trial · Interventional
Cervical Cancer Detection Using Optical Spectroscopy
NCT00900575CI-TRIAL-00104912recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of the work described in this protocol is to determine the optical signatures of cervical dysplasia using optical technologies.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Optical Spectroscopy Bench-Top System | Device | — | UNRESOLVED |
| Portable Optical Spectrometer | Device | — | UNRESOLVED |
| Transvaginal colposcope | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Colposcope
- description
- Patients referred for GYN procedures. Specifically, patients will be referred for Pap smear, colposcope or LEEP. The intervention for this arm is the use of the bench-top, miniature optical spectrometer or trans-vaginal colposcope
- interventionNames
- Device: Optical Spectroscopy Bench-Top System
- Device: Portable Optical Spectrometer
- Device: Transvaginal colposcope
Primary outcomes (1)
- measure
- Identification of optical signatures of cervical tissue
- timeFrame
- Day of procedure (less than 10 minutes)
- description
- The primary outcome of this study is the identification of the optical signatures of cervical tissue.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * undergoing colposcopy for the diagnosis of cervical cancer * LEEP for the treatment of cervical cancer in early stages. * Follow-up Pap smear in surveillance Exclusion Criteria: * Women under the age of 18 (minors) will be excluded from this study. * patients will be excluded if she has had a recent episode of bleeding or preterm labor. * Subjects who are not competent to give consent will excluded
References
Publications (2)
- RESULTChang VT, Cartwright PS, Bean SM, Palmer GM, Bentley RC, Ramanujam N. Quantitative physiology of the precancerous cervix in vivo through optical spectroscopy. Neoplasia. 2009 Apr;11(4):325-32. doi: 10.1593/neo.81386. PMID 19308287
- DERIVEDAsiedu MN, Agudogo JS, Dotson ME, Skerrett E, Krieger MS, Lam CT, Agyei D, Amewu J, Asah-Opoku K, Huchko M, Schmitt JW, Samba A, Srofenyoh E, Ramanujam N. A novel speculum-free imaging strategy for visualization of the internal female lower reproductive system. Sci Rep. 2020 Oct 6;10(1):16570. doi: 10.1038/s41598-020-72219-9. PMID 33024146