Clinical trial · Observational
Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma
A Children?s Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens
NCT00899275CI-TRIAL-00070162completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to collect and store samples of blood and tumor tissue from patients with osteosarcoma. Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Osteosarcoma | Osteosarcoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cytology Specimen Collection Procedure | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Ancillary-correlative
- description
- After the initial submission of blood samples, patients may undergo open or closed biopsy in order to obtain fresh and frozen tissue samples as well as paraffin embedded material. Patients who are enrolled at the time of initial diagnosis but then have a definitive surgery or develop recurrent disease may submit additional samples (paraffin block, frozen and fresh tumor tissue, or slides together with blood samples). Autopsy tumor samples may also be submitted.
- interventionNames
- Other: Cytology Specimen Collection Procedure
Primary outcomes (1)
- measure
- Collection of biological specimens from patients with osteosarcoma
- timeFrame
- Baseline
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * All osteosarcoma patients seen at COG institutions are eligible, including the following: * Newly diagnosed patients * Patients with recurrent disease who were not enrolled at the time of diagnosis * The following specimens from the initial biopsy (and/or definitive surgery if an up-front resection is performed) are required: * Paraffin embedded block OR 30 unstained slides * Pretreatment blood consisting of 5 mL serum, 10 mL plasma, and 10 mL heparinized whole blood * Fresh and frozen tumor specimens * Patients are not required to enter a therapeutic study to enroll on this study
References
Publications (0)
Data not yet available
No reference posted for this study.