Gene and Protein Expression Patterns in Predicting Response to Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer

Arms (1)

1. label

   head and neck cancer patients

   interventionNames

   1. Genetic: DNA and tissue microarray analysis
   2. Genetic: reverse transcriptase-polymerase chain reaction
   3. Other: mass spectrometry

Primary outcomes (3)

1. measure

   Identification of 100 patients from the Head and Neck (H&N) Tumor Tissue Repository and Clinical Database treated with cetuximab or cetuximab-containing combination therapy as a standard of care

   timeFrame

   approximately three years from enrollment of first patient

2. measure

   Gene and protein expression patterns in selected H&N Tumor Tissue Repository and Clinical Database patients

   timeFrame

   upon colleciton of final patient data

3. measure

   Predictive patterns of gene and protein expression associated with cetuximab treatment response and survival

   timeFrame