Clinical trial · Observational
DNA Analysis of Tissue Samples From Patients With Head and Neck Cancer
Genetic Analysis of Head and Neck Squamous Cell Carcinoma
NCT00898664CI-TRIAL-00009870completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This laboratory study is looking at DNA in tissue samples from patients with head and neck cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cytogenetic analysis | Genetic | — | UNRESOLVED |
| gene expression analysis | Genetic | — | UNRESOLVED |
| immunohistochemistry staining method | Other | — | UNRESOLVED |
| laboratory biomarker analysis | Other | — | UNRESOLVED |
| mutation analysis | Genetic | — | UNRESOLVED |
| polymerase chain reaction | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (5)
- measure
- Assess common genetic mutations in tumor and germline DNA samples
- timeFrame
- Upon collection of final patient data
- measure
- Viral DNAs related to demographics, tumor characteristics, and patient prognosis
- timeFrame
- Upon collection of final patient data
- measure
- Novel viral sequences and cancer-associated gene mutations in young nonsmoking patients with head and neck squamous cell carcinoma and in other distinct head and neck cancers
- timeFrame
- Upon collection of final patient data
- measure
- Tumor suppressor gene mutations related to gene expression data
- timeFrame
- upon collection of final patient data
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient with head and neck squamous cell carcinoma (HNSCC) enrolled in the Head and Neck Tissue Repository * Sufficient biological material collected to perform study tests * Historical material available from excess tissues at the Vanderbilt Pathology Department Exclusion Criteria: * Not specified PRIOR CONCURRENT THERAPY: * Not specified
References
Publications (0)
Data not yet available
No reference posted for this study.