Clinical trial · Observational
Serum and Exhaled Breath Condensate MALDI-MS of Lung Cancer. (SPORE)
Serum and Exhaled Breath Condensate MALDI-MS of Lung Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): This study competed with another VICC study
Summary
Brief summary (as posted)
RATIONALE: Collecting and storing samples of blood and exhaled breath from patients with cancer and from healthy participants to study in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is collecting and analyzing samples of blood and exhaled breath from patients who have or are at high risk for lung cancer and from healthy participants.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| biologic sample preservation procedure | Other | — | UNRESOLVED |
| laboratory biomarker analysis | Other | — | UNRESOLVED |
| matrix-asst laser desorption/ionization time flight mass spectrometry | Other | — | UNRESOLVED |
| protein expression analysis | Genetic | — | UNRESOLVED |
| proteomic profiling | Genetic | — | UNRESOLVED |
| questionnaire administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Health Volunteers
- description
- Blood and exhaled breath condensate will be collected.
- interventionNames
- Genetic: protein expression analysis
- Genetic: proteomic profiling
- Other: biologic sample preservation procedure
- Other: laboratory biomarker analysis
- Other: matrix-asst laser desorption/ionization time flight mass spectrometry
- Other: questionnaire administration
- label
- Patients at risk or already identified as having lung cancer
- description
- Blood and exhaled breath condensate will be collected.
- interventionNames
- Genetic: protein expression analysis
- Genetic: proteomic profiling
- Other: biologic sample preservation procedure
- Other: laboratory biomarker analysis
- Other: matrix-asst laser desorption/ionization time flight mass spectrometry
- Other: questionnaire administration
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Meets 1 of the following criteria: * Normal healthy volunteer * At high risk for lung cancer (e.g., \> 30-pack year history of smoking; chronic obstructive pulmonary disease; or disease-free after surgical resection of lung cancer) * Diagnosis of stage I, II, IIIA, IIIB, or IV lung cancer * Must be willing to allow blood and exhaled breath condensate samples to be stored for genetic testing PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified
References
Publications (0)
Data not yet available