Clinical trial · Observational
Study of Stored Tumor Samples in Young Patients With Brain Tumors
Molecular and Histopathologic Characterization of Atypical Teratoid Rhabdoid Tumors, Choroid Plexus Carcinomas, Ependymomas, Medulloblastoma HGNET, CNS Embryonal Tumors and Gliomas of the Pediatric CNS
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): New Protocol that replaces the current study
Summary
Brief summary (as posted)
This laboratory study is looking at stored tumor samples in young patients with brain tumors. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain and Central Nervous System Tumors | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Tumor/Tissue Sample
- description
- Tumor material collected prospectively from a clinically well characterized patient cohort
Primary outcomes (1)
- measure
- Relationship between molecular abnormalities and tumor histologic and clinical characteristics
- timeFrame
- 20 Years
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 39 Years
Show eligibility criteria text
Inclusion Criteria * Tumor may be primary, progressive or recurrent CNS tumor including brain and/or spine. All tumor types will be included with a focus on medulloblastoma, HGNET, CNS embryonal tumors, gliomas, ependymoma, CPC and ATRT tumors. Low grade gliomas are currently very challenging to culture and implant but if techniques mature these will also be included. Although rare, patients with ATRT may present with a primary renal and CNS tumor. In these instances samples will be collected from both the kidney and CNS tumor for analysis if available. * Tumor may be collected at surgery prior to histologic confirmation * Age less than 40 years at the time of initial diagnosis. * Enrollment in the current version of the institution's banking protocol Exclusion Criteria * Diagnosis of tumor outside the central nervous system. * Age greater than or equal to 40 years at the time of diagnosis
References
Publications (0)
Data not yet available