Clinical trial · Observational

Oral HPV Infection in Young Men

Human Papillomavirus Infection of the Mouth in Young Men and Risk Factors for Oropharyngeal Cancer

NCT00897273CI-TRIAL-00036615completedClinicalTrials.gov clinicaltrialsPublishedExplore in graph →

Summary

Brief summary (as posted)

RATIONALE: Gathering information about human papillomavirus infection of the mouth in young men may help doctors learn more about risk factors for oropharyngeal cancer. PURPOSE: This research study is assessing human papillomavirus infection of the mouth in young men and risk factors for oropharyngeal cancer.

Conditions

Conditions (3)

Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.

Condition (as posted)	Mapped entity	Match	Confidence
Head and Neck Cancer	Malignant Head and Neck Neoplasm	ALIAS	0.90
Infection	—	UNRESOLVED	—
Precancerous Condition	—	UNRESOLVED	—

Interventions

Interventions (5)

Intervention	Type	Mapped drug	Match
comparative genomic hybridization	Genetic	—	UNRESOLVED
evaluation of cancer risk factors	Procedure	—	UNRESOLVED
gene expression analysis	Genetic	—	UNRESOLVED
study of high risk factors	Procedure	—	UNRESOLVED
study of socioeconomic and demographic variables	Other	—	UNRESOLVED

Design

Arms and outcomes

Arms (0)

[]

Primary outcomes (2)

measure
Presence of an oral human papillomavirus (HPV) type 16, 18, 6 or 11 infection
timeFrame
2 years
measure
Presence of oral HPV infection by any of 37 HPV types
timeFrame
2 years

Eligibility

Eligibility (as posted)

Sex: Male
Minimum age: 18 Years
Maximum age: 21 Years

Show eligibility criteria text

DISEASE CHARACTERISTICS:

* Currently enrolled at one of the following institutions:

  * Johns Hopkins University
  * University of Maryland
  * Towson University

PATIENT CHARACTERISTICS:

* Able to understand the procedures and the potential risks involved as determined by clinic staff

PRIOR CONCURRENT THERAPY:

* No prior Gardasil® off label

References

Publications (1)

RESULTGillison ML. Human papillomavirus-related diseases: oropharynx cancers and potential implications for adolescent HPV vaccination. J Adolesc Health. 2008 Oct;43(4 Suppl):S52-60. doi: 10.1016/j.jadohealth.2008.07.002. PMID 18809146