Clinical trial · Observational
Collecting and Analyzing Tissue Samples From Patients Undergoing Surgery for Non-Small Cell Lung Cancer
Molecular Fingerprinting of Lung Cancer
NCT00897117CI-TRIAL-00123116recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that may occur in RNA and identify biomarkers related to cancer. PURPOSE: This research study is collecting and analyzing lung tissue samples from patients undergoing surgery for non-small cell lung cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| biologic sample preservation procedure | Other | — | UNRESOLVED |
| gene expression analysis | Genetic | — | UNRESOLVED |
| laboratory biomarker analysis | Other | — | UNRESOLVED |
| matrix-assisted laser desorption/ionization time of flight mass spectrometry | Other | — | UNRESOLVED |
| microarray analysis | Genetic | — | UNRESOLVED |
| protein expression analysis | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Resectable non-small cell lung cancer
- description
- Patients with clinical stage I or II invasive lung cancer that can be completely removed by surgery and who have not undergone chemotherapy or radiotherapy before surgery
- interventionNames
- Genetic: gene expression analysis
- Genetic: microarray analysis
- Genetic: protein expression analysis
- Other: biologic sample preservation procedure
- Other: laboratory biomarker analysis
- Other: matrix-assisted laser desorption/ionization time of flight mass spectrometry
Primary outcomes (1)
- measure
- Protein and RNA expression fingerprints from collected samples
- timeFrame
- after collection of designated samples
Secondary outcomes (2)
- measure
- Development of statistical and computational methods to model relationship of data and clinical outcomes
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 120 Years
Show eligibility criteria text
Inclusion criteria * Diagnosis of non-small cell lung cancer * Clinical stage I and II disease * Resectable disease and complete surgical resection planned * Treated on companion studies at Vanderbilt University, the Veterans Administration hospital, St. Thomas, and Vanderbilt-Ingram Cancer Center Affiliate Network * Tumor specimen samples must be available at resection Exclusion criteria * Chemotherapy before surgery * Radiotherapy before surgery
References
Publications (0)
Data not yet available
No reference posted for this study.