Clinical trial · Observational
Study of Metabolic Syndrome in Young Patients Who Are Acute Lymphoblastic Leukemia Survivors and Their Healthy Siblings
Health Effects After Leukemia (HEAL) Research Study
NCT00897078CI-TRIAL-00010713completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Gathering information about metabolic syndrome from young patients who have survived acute lymphoblastic leukemia (ALL) may help doctors learn more about the disease. PURPOSE: This phase I trial is studying the metabolic syndrome in young patients who have survived acute lymphoblastic leukemia and in healthy sibling volunteers.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Leukemia | Leukemia | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| assessment of therapy complications | Procedure | — | UNRESOLVED |
| laboratory biomarker analysis | Other | — | UNRESOLVED |
| medical chart review | Other | — | UNRESOLVED |
| metabolic assessment | Other | — | UNRESOLVED |
| questionnaire administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Prevalence of the metabolic syndrome (MS) and its component traits in these patients and in healthy volunteers
- timeFrame
- 2009-2011
- measure
- Host- and treatment-related risk factors for MS
- timeFrame
- 2009-2011
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 8 Years
- Maximum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria:
DISEASE CHARACTERISTICS:
* Meets one of the following eligibility criteria:
* Childhood acute lymphoblastic leukemia survivor
* Less than 22 years old at diagnosis
* Treated from 1990-2007 at one of the following locations:
* Fred Hutchinson Cancer Research Center and/or Children's Hospital and Regional Medical Center in Seattle, WA
* Vanderbilt Children's Hospital in Nashville, TN
* Meets 1 of the following treatment criteria:
* Completed conventional therapy ≥ 11 months ago and in first complete remission
* Received an allogeneic hematopoietic cell transplantation ≥ 11 months ago and in complete remission
* No evidence of recurrent disease
* Healthy volunteer
* Full sibling of enrolled cancer survivor
* Age 8-21 (if more than 1 eligible sibling, sibling of closest age is preferred)
* No history of cancer
PATIENT CHARACTERISTICS:
* Able to speak, read, and write English
PRIOR CONCURRENT THERAPY:
* See Disease Characteristics
* No active treatment for graft-vs-host disease
Exclusion Criteria:
* Lack of ability to speak, read, and write English
* Active treatment for graft versus host diseaseReferences
Publications (0)
Data not yet available
No reference posted for this study.