Clinical trial · Observational
Study of Breast Tissue in Women Not Previously Diagnosed With Breast Cancer Who Are Undergoing Fine Needle Aspiration
Gene Methylation and Estradiol Levels in Random FNA Samples as Biomarkers for Breast Cancer Risk
NCT00896636CI-TRIAL-00046866unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Studying samples of blood and breast tissue from healthy women in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to breast cancer risk. PURPOSE: This research study is looking at breast tissue in women not previously diagnosed with breast cancer who are undergoing fine-needle aspiration.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Healthy, no Evidence of Disease | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Mammogram | Other | — | UNRESOLVED |
| Random fine need aspiration (rFNA) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Luteal
- description
- Pre-menopausal women who undergo rFNA procedure during the luteal phase of their menstrual cycle.
- interventionNames
- Procedure: Random fine need aspiration (rFNA)
- Other: Mammogram
- label
- Follicular
- description
- Pre-menopausal women who undergo rFNA procedure during the follicular phase of their menstrual cycle.
- interventionNames
- Procedure: Random fine need aspiration (rFNA)
- Other: Mammogram
- label
- Menopause
- description
- Women who have entered menopause.
- interventionNames
- Procedure: Random fine need aspiration (rFNA)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 35 Years
- Maximum age
- 60 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Women meeting one of the following requirements: * Regularly cycling premenopausal women under 45 years of age * Perimenopausal women 45-55 years of age who have had ≥ two periods in the past 6 months * Postmenopausal women under 60 years of age (no menstrual period for 12 months and follicle-stimulating hormone (FSH) levels \> 25 IU/dL) * No history of breast cancer diagnosis or prior treatment for breast cancer * Negative breast evaluation within the past 3 months PATIENT CHARACTERISTICS: * See Disease Characteristics PRIOR CONCURRENT THERAPY: * No concurrent oral contraceptives * At least 2 weeks since prior aspirin, non-steroidal anti-inflammatory drugs, and vitamin E
References
Publications (0)
Data not yet available
No reference posted for this study.