Clinical trial · Interventional
Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD)
Laparoscopic Nissen Fundoplication Combined With Posterior Gastropexy in Surgical Treatment of Gastroesophageal Reflux Disease
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Laparoscopic Nissen Fundoplication has established itself as the procedure of choice in the surgical management of the majority of patients suffering from gastroesophageal reflux disease (GERD). Postoperative paraesophageal herniation has incidence ranges up to 7% in the immediate postoperative period. This randomized controlled study was scheduled to investigate the role of the posterior gastropexy, in combination with laparoscopic Nissen fundoplication, in prevention of paraesophageal herniation and improvement of postoperative results, in surgical treatment of GERD.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Barrett's Esophagus | — | UNRESOLVED | — |
| Dysphagia | — | UNRESOLVED | — |
| Esophagitis | — | UNRESOLVED | — |
| Gastroesophageal Reflux Disease | — | UNRESOLVED | — |
| Hiatal Hernia | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Gastropexy | Procedure | — | UNRESOLVED |
| Nissen | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Nissen
- description
- Laparoscopic Nissen Fundoplication
- interventionNames
- Procedure: Nissen
- type
- ACTIVE_COMPARATOR
- label
- Gastropexy
- description
- Procedure/Surgery Laparoscopic Nissen Fundoplication combined with posterior gastropexy
- interventionNames
- Procedure: Nissen
- Procedure: Gastropexy
Primary outcomes (1)
- measure
- Laparoscopic Nissen fundoplication combined with posterior gastropexy may prevent postoperative paraesophageal or sliding herniation in surgical treatment of GERD
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Age \>18 years * Indications for surgical treatment of GERD * ASA I, II Exclusion Criteria: * ASA III, IV * Previous gastric procedures * Conversion to open procedure
References
Publications (1)
- DERIVEDTsimogiannis KE, Pappas-Gogos GK, Benetatos N, Tsironis D, Farantos C, Tsimoyiannis EC. Laparoscopic Nissen fundoplication combined with posterior gastropexy in surgical treatment of GERD. Surg Endosc. 2010 Jun;24(6):1303-9. doi: 10.1007/s00464-009-0764-0. Epub 2009 Dec 4. PMID 19960205