Clinical trial · Interventional
Study of Saline Linked Monopolar Surface Radiofrequency (RF) Ablation of Hepatic Tumors
Phase I Study of Saline Linked Monopolar Surface Radiofrequency (RF) Ablation of Hepatic Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
* To determine the depth of coagulation which is possible in human liver tissue using the saline linked RF Surface ablation with the Tissue Link floating ball. * To determine the efficacy of the technique on surface liver tumors using saline linked RF surface ablati * To determine a safe (non-popping upper limit) of power per area that will permit a 1 cm depth of tissue destruction without inflow occlusion an da 2 cm depth with inflow occlusion.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Liver Metastases From Colorectal Cancer | — | UNRESOLVED | — |
| Malignant Liver Tumors | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| RF Ablation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Single group
- interventionNames
- Procedure: RF Ablation
Primary outcomes (2)
- measure
- Depth of coagulation which is possible in human liver tissue using the saline linked RF Surface ablation with the Tissue Link floating ball
- timeFrame
- Day 1
- description
- On day of surgery
- measure
- Efficacy of the technique on surface liver tumors using saline lined RF Surface ablation.
- timeFrame
- Day 1
- description
- On day of surgery
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Eligibility for Stage I (Normal Liver Tissue) * Resectable liver metastases from malignant liver tumors, primary or secondary * Patient has been scheduled for liver resection and is in generally good medical condition * No evidence of extra-hepatic disease * Patient does not have a pacemaker * Age \>= 18 * Able to provide informed consent Eligibility for Stage II (Patients with liver metastases from colorectal cancer) * Resectable liver metastases from colorectal cancer * Patient has been scheduled for liver resection is in generally good medical condition * No evidence of extra-hepatic disease. * Patient does not have a pacemaker * Age \>= 18 * Able to provide informed consent
References
Publications (1)
- DERIVEDGnerlich JL, Ritter JH, Linehan DC, Hawkins WG, Strasberg SM. Saline-linked surface radiofrequency ablation: a safe and effective method of surface ablation of hepatic metastatic colorectal cancer. Ann Surg. 2009 Jul;250(1):96-102. doi: 10.1097/SLA.0b013e3181ae91af. PMID 19561459