Clinical trial · Interventional
In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
Clinical Research Study on in Vitro Maturation With IVF Compared to Mild Stimulation IVF
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): investigator changed location, requires new training effort
Summary
Brief summary (as posted)
Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation doses. The goal of the research is to determine which of these if more suitable as a low cost approach for varying individual patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Infertility | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| In vitro maturation and in vitro fertilization | Procedure | — | UNRESOLVED |
| Low doses of gonadotropin stimulation. | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- IVM
- description
- Early egg retrieval, in vitro maturation, then IVF
- interventionNames
- Procedure: In vitro maturation and in vitro fertilization
- type
- ACTIVE_COMPARATOR
- label
- Mild IVF
- description
- Mild gonadotropin and conventional IVF
- interventionNames
- Procedure: Low doses of gonadotropin stimulation.
Primary outcomes (1)
- measure
- Cost effectiveness
- timeFrame
- two years
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 21 Years
- Maximum age
- 41 Years
Show eligibility criteria text
Inclusion Criteria: * Under age 42 female, normal uterine cavity, BMI 18-34kg/m2, Exclusion Criteria: * Donor eggs, donor sperm, myoma over 5 cm * Current hydrosalpinx, abnormal uterine cavity.
References
Publications (2)
- BACKGROUNDSon WY, Chung JT, Herrero B, Dean N, Demirtas E, Holzer H, Elizur S, Chian RC, Tan SL. Selection of the optimal day for oocyte retrieval based on the diameter of the dominant follicle in hCG-primed in vitro maturation cycles. Hum Reprod. 2008 Dec;23(12):2680-5. doi: 10.1093/humrep/den332. Epub 2008 Sep 4. PMID 18775885
- BACKGROUNDSon WY, Chung JT, Demirtas E, Holzer H, Sylvestre C, Buckett W, Chian RC, Tan SL. Comparison of in-vitro maturation cycles with and without in-vivo matured oocytes retrieved. Reprod Biomed Online. 2008 Jul;17(1):59-67. doi: 10.1016/s1472-6483(10)60294-5. PMID 18616892