Clinical trial · Interventional
Anastomotic Techniques in Pancreaticoduodenectomy
A Randomised Controlled Trial of Pancreaticogastrostomy Versus Pancreaticojejunostomy in Reconstruction After Pancreaticoduodenectomy for Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
There are two principal ways of draining the remnant of the pancreas back into the intestine after removal of the head of the pancreas for cancer. This can be performed either to the jejunum or to the stomach. The aim of this study is to randomly allocate consenting patients to one of the two arms to study whether the leak rates from the anastomosis and the outcomes after the surgery are affected. Previous papers have shown similar results in both groups although non randomized data suggested that the Pancreaticogastrostomy (drainage into the stomach) may be superior
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
| Pancreatic Fistula | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| type of anastomosis after pancreaticoduodenectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- 1
- description
- Pancreaticojejunostomy for reconstruction after pancreaticoduodenectomy
- interventionNames
- Procedure: type of anastomosis after pancreaticoduodenectomy
- type
- ACTIVE_COMPARATOR
- label
- 2
- description
- Pancreaticogastrostomy for reconstruction after pancreaticoduodenectomy
- interventionNames
- Procedure: type of anastomosis after pancreaticoduodenectomy
Primary outcomes (1)
- measure
- pancreatic fistula rate
- timeFrame
- 30 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Pancreaticoduodenectomy for adenocarcinoma of the pancreatic head 2. resectable tumour Exclusion Criteria: 1. chronic pancreatitis/benign tumours- 2. tumours extending into the body of the pancreas 3. tumours with metastasis beyond regional lymph nodes 4. requirement for sub total pancreatectomy 5. prolonged hypotension - \< 80 mm of hg for more than 30 min
References
Publications (0)
Data not yet available