Clinical trial · Interventional
Detection of Early Gastric Cancers Using Confocal Laser Endomicroscopy
Comparison Confocal Laser Endomicroscopy With Conventional Endoscopy for the Detection of Early Gastric Cancers
NCT00851305CI-TRIAL-00007449CLEcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine whether endomicroscopy can improve the detection of Early Gastric Cancers (EGC).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Precancerous Conditions | — | UNRESOLVED | — |
| Stomach Neoplasms | Gastric Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endomicroscope (Pentax, Tokyo, Japan) | Device | — | UNRESOLVED |
| Gastroscopes (Pentax, Tokyo, Japan) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- 1 confocal laser endomicroscopy
- description
- Targeted biopsies are performed when the lesion was considered as IM, dysplasia or carcinoma by confocal laser endomicroscopy.
- interventionNames
- Device: Endomicroscope (Pentax, Tokyo, Japan)
- type
- ACTIVE_COMPARATOR
- label
- 2 Conventional endoscopy
- description
- Routine biopsies are performed when the lesion was considered as IM, dysplasia or carcinoma by conventional endoscopy.
- interventionNames
- Device: Gastroscopes (Pentax, Tokyo, Japan)
Primary outcomes (1)
- measure
- To compare the rate of EGCs/GCs using CLE versus conventional gastroscopy.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 45 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * 45 years old ≤ age \< 80 years old * Patients with dyspeptic symptoms or with gastric premalignant conditions for surveillance gastroscopy Exclusion Criteria: * Known cancers or gastrectomy * Scheduled for endoscopic treatment * Alarm symptoms such as dysphagia, anaemia, gastrointestinal bleeding or obstruction, marked weight loss * Under conditions such as: * ascites * jaundice * liver cirrhosis * impaired renal function * coagulopathy * fever * pregnancy * breastfeeding * Inability to provide informed consent * Known allergy to fluorescein sodium
References
Publications (0)
Data not yet available
No reference posted for this study.