Clinical trial · Observational
Functional Imaging in HNC Undergoing Chemoradiation
Investigation of the Role of Functional Imaging in Characterising Radiotherapy Target Volumes and Assessing Disease Response in Patients Undergoing Chemoradiation for Head and Neck Cancer (HNC)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to generate a library of functional imaging and anatomical imaging for patients with head and neck cancers for evaluation of new radiotherapy strategies and planning techniques including IMRT. Secondary aims would be to observe the changes in the cancers as the treatment progresses as well as to define the biologically most active part of the tumor (biological target volume) which could be given more intensive treatment. Tumor volumes seen on different imaging modalities will be compared with a hope of finding an optimal imaging methodology for accurate visualization of the head and neck cancers
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- the number of patients completing the study protocol and adding to the library of images to be used for evaluation of new radiotherapy strategies and planning techniques including IMRT
Secondary outcomes (3)
- measure
- the ability to define a biological target volume in all the patients
- measure
- to compare the volumes defined by the conventional imaging to the functional imaging
- measure
- to measure changes in the volume of the disease with diff
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * patients with histologically proven head and neck cancer, planed for chemotherapy and radiotherapy * age more than 18 years * patient willing to participate and has signed a consent form * patients in good physical status (WHO performance status 0-2) Exclusion Criteria: * patients in poor health (WHO performance status \>2) * patients with any other cancer apart from skin cancer * patients with contraindications to MRI scan and IV contrast * diabetic patients * patients with renal failure
References
Publications (0)
Data not yet available