Clinical trial · Interventional
Treatment of Meibomian Gland Dysfunction and Evaporative Dry Eye
Randomized Clinical Trial for Treatment of Meibomian Gland Dysfunction and Evaporative Dry Eye
NCT00832130CI-TRIAL-00005913completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this study is to evaluate the clinical utility, safety and effectiveness of the Manual Mini System compared to standardized warm compress therapy for application of controlled, localized heat therapy in adult patients with chronic cystic conditions of the eyelids, including meibomian gland dysfunction, also known as evaporative dry eye or lipid deficiency dry eye, and chalazia.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chalazion | — | UNRESOLVED | — |
| Dry Eye Syndromes | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| iHeat Portable Warm Compress Therapy | Device | — | UNRESOLVED |
| Manual Mini System | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Manual Mini System
- description
- Treatment with experimental Manual Mini System
- interventionNames
- Device: Manual Mini System
- type
- ACTIVE_COMPARATOR
- label
- Warm Compress Therapy
- description
- Control group receiving warm compress therapy in first study phase and crossover Manual Mini System treatment in second study phase
- interventionNames
- Device: Manual Mini System
- Device: iHeat Portable Warm Compress Therapy
Primary outcomes (3)
- measure
- Meibomian Gland Assessment (Total Meibomian Gland Secretion Score)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * At least 18 years of age. * Meibomian gland obstruction * Dry eye symptoms * Willingness to comply with study procedures and return for all visits Exclusion Criteria: * Ocular surgery, injury, or herpes infection within past 3 months * Active ocular infection * Active ocular inflammation or recurrent inflammation within past 3 months * Moderate to severe allergic conjunctivitis * Severe eyelid inflammation * Eyelid abnormalities that affect lid function * Ocular surface abnormalities that may compromise corneal integrity * Macular disease * Systemic disease condition or medication that causes dry eye * Use of other treatments for meibomian gland dysfunction or dry eye * Pregnant or nursing women * Participation in another ophthalmic clinical trial within past 30 days
References
Publications (0)
Data not yet available
No reference posted for this study.