Clinical trial · Interventional
Total Hemihepatic Vascular Exclusion in Hepatectomy in Hepatocellular Carcinoma Treatment
A Prospective Randomized Controlled Trial of Total Hemihepatic Vascular Exclusion in Hepatectomy in Hepatocellular Carcinoma Treatment
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Total hemihepatic vascular exclusion(THHVE),completely isolates the right or left hemiliver ipsilateral to the lesion that requires resection from the systemic circulation,has the advantage of preventing backflow hemorrhage or air embolism without having to resort to caval blood flow interruption of THVE.This study is to evaluate if THHVE can raduce bleeding,reduce the incidence of complications and improve the patient's free survival and overall survival compared with hemihepatic vascular clamping and Pringle maneuver.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Hemihepatic vascular Clamping | Procedure | — | UNRESOLVED |
| Pringle's Maneuver | Procedure | — | UNRESOLVED |
| Total hemihepatic vascular exclusion | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Total Hemihepatic Vascular Exclusion
- description
- Patients with HCC received Total Hemihepatic Vascular Exclusion in hepatectomy.
- interventionNames
- Procedure: Total hemihepatic vascular exclusion
- type
- EXPERIMENTAL
- label
- Hemihepatic vascular Clamping
- description
- Patients with HCC received Hemihepatic vascular Clamping in hepatectomy.
- interventionNames
- Procedure: Hemihepatic vascular Clamping
- type
- EXPERIMENTAL
- label
- Pringle's Maneuver
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
5Inclusion Criteria: * Understanding and being willing to sigh the informed consent form. * Aged 18-75years. * Corresponding to diagnostic standards of HCC, without any adjuvant therapy,tumor or multiple tumors located in right or left liver lobe. * The function of heart, lung ,renal is well,without any surgery contraindication. * KPS score≥60分 * Liver function in the Child-Pugh classification is A or B. * Tumor AJCC stage isⅠorⅡ. Exclusion Criteria: * cannot be follow-up * liver function in the Child-Pugh classification is C. * with tumor thrombus in the hepatic vein or main trunk of portal vein * with extrahepatic metastasis
References
Publications (0)
Data not yet available