Clinical trial · Interventional
Randomized Trial Comparing Endoscopy and Surgery for Pancreatic Cyst-gastrostomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients with pancreatitis can develop inflammatory fluid collection around the pancreas called pseudocysts. Pseudocysts may cause abdominal pain when they are more than 6cm in size. These pseudocysts can be treated (drained) by surgery or by endoscopy. Both treatment options are the current standard-of-care at all institutions around the World. The aim of this study is to identify the better of the two techniques, surgery versus endoscopy, for treatment of patients with pancreatic pseudocysts. This will be done by comparing a) the rates of pseudocyst recurrence b) quality of life of patients following treatment and c) cost associated with treatment, between both treatment modalities.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Pseudocysts | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic cyst-gastrostomy | Procedure | — | UNRESOLVED |
| Surgical cyst-gastrostomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- 1
- description
- Endoscopic cyst-gastrostomy with a neurolytic block along with oral/transdermal analgesic therapy
- interventionNames
- Procedure: Endoscopic cyst-gastrostomy
- type
- ACTIVE_COMPARATOR
- label
- 2
- description
- Surgical cyst-gastrostomy with neurolytic block and pain managed by only oral/transdermal analgesic
- interventionNames
- Procedure: Surgical cyst-gastrostomy
Primary outcomes (1)
- measure
- Compare median time to pseudocyst recurrence between patients undergoing EUS or Surgical Cysto-gastrostomy
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * age \> 19yrs * able to provide informed consent * pancreatic pseudocyst by CT Exclusion Criteria: * age \< 19yrs * unable to consent * pancreatic abscess or necrosis
References
Publications (1)
- DERIVEDVaradarajulu S, Bang JY, Sutton BS, Trevino JM, Christein JD, Wilcox CM. Equal efficacy of endoscopic and surgical cystogastrostomy for pancreatic pseudocyst drainage in a randomized trial. Gastroenterology. 2013 Sep;145(3):583-90.e1. doi: 10.1053/j.gastro.2013.05.046. Epub 2013 May 31. PMID 23732774