Clinical trial · Observational
SS-GCC1- Screening Study of Genetic Changes in Colorectal Cancer
NCT00825110CI-TRIAL-00040630unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
the principal research objective is to form a database of tissue samples from patients with colorectal (bowel) cancer. The tissue samples that will be used for this research will have already been taken for diagnostic or therapeutic reasons. We will also be asking for consent for a research blood sample. The database will be used to improve our understanding of the molecular genetics and gene expression patterns in colorectal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- No treatment
- description
- confirmed diagnosis of colorectal carcinoma
Primary outcomes (1)
- measure
- the primary endpoint is the identification of cases with evidence of loss of the product of one of the four main MMR genes on tumour histology.
Secondary outcomes (1)
- measure
- Secondary outcome measure is the survival and response to treatment of the identified cases.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * adults who have a terminal illness * 18 and over * confirmed diagnosis of colorectal carcinoma * ability to give informed consent * paraffin embedded histological material available for analysis Exclusion Criteria: * medical or psychiatric conditions * impairing ability to give informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.