Clinical trial · Interventional
Exploratory Study of Natural Killer Cells in Human Skin
NCT00824889CI-TRIAL-00015501completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Natural Killer (NK) cells play a unique role during innate immune responses as they are able to recognize and eliminate, without specific sensitization, tumors, microbe-infected cells as well as allogeneic cells.In a first time, we will characterize the tissue distribution, the phenotype and the effector functions of NK cells present in the human healthy skin.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Atopic Dermatitis | — | UNRESOLVED | — |
| Contact Dermatitis | — | UNRESOLVED | — |
| Graft Versus Host Disease | — | UNRESOLVED | — |
| Lichen Planus | — | UNRESOLVED | — |
| Melanoma | Melanoma | ONTOLOGY_EXACT | 0.98 |
| Psoriasis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Biopsy and sample of blood | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (7)
- type
- OTHER
- label
- 1
- description
- Healthy volunteer
- interventionNames
- Other: Biopsy and sample of blood
- type
- OTHER
- label
- 2
- description
- atopic dermatitis patient
- interventionNames
- Other: Biopsy and sample of blood
- type
- OTHER
- label
- 3
- description
- contact dermatitis patient
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥ 18 years. * Consent obtained after healthy donor or patient information. * Patients suffering from one of the following diseases: a) atopic dermatitis ; b) contact dermatitis; c) psoriasis ; d) lichen planus ; e) GVH ; f) melanoma. Exclusion Criteria: * Age below 18, * pregnant or breastfeeding women, * persons under guardianship, persons without social security, prisoners, persons hospitalized without consent on the basis of French laws L. 3212-1 et L. 3213-1. Patients affected by HIV infection, AIDS, Hepatitis A, B or C infection. * Neutropenia \<1000/mm3. * Thrombopenia \<50 000/mm3.
References
Publications (0)
Data not yet available
No reference posted for this study.