Clinical trial · Interventional
Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses
NCT00814528CI-TRIAL-00034765withdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): The study never started due to the Principal Investigator leaving the institution
Summary
Brief summary (as posted)
The purpose of this study is to compare the treatment of skin growths called actinic keratoses (AK) with 5-ALA PDT, an FDA-approved treatment, versus treatment with other conventionally used FDA-approved agents such as cryotherapy, Imiquimod, or 5-fluorouracil (5-FU).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Actinic Keratosis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 5-ALA plus Blu-Light | Drug | — | UNRESOLVED |
| 5-FU, Imiquimod or treatment with cryotherapy | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- 1
- description
- Application of 5-ALA PDT to some lesions on skin with "Blue U" light source (417 nm).
- interventionNames
- Drug: 5-ALA plus Blu-Light
- type
- EXPERIMENTAL
- label
- 2
- description
- 5-FU, Imiquimod or treatment with cryotherapy to lesions on the skin.
- interventionNames
- Drug: 5-FU, Imiquimod or treatment with cryotherapy
Primary outcomes (1)
- measure
- Actinic keratosis /incomplete therapy and reoccurence
- timeFrame
- 18 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 95 Years
Show eligibility criteria text
Inclusion Criteria: * 18-95 years old * Diagnosied with actinic keratoses. Exclusion Criteria: * Patients who have had Isotretinoin therapy less that 1 year prior to screening. * Patients who have an adverse reaction to light exposure (for example photo- exacerbated seizures). * History of porphyria
References
Publications (0)
Data not yet available
No reference posted for this study.