Clinical trial · Interventional
The Effect on an Ionic Silver Dressing in Head and Neck Patients With Malignant Fungating Wound
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Background. Malignant fungating wounds(MFW) are caused by cancerous cells invading skin tissue, which exhibit increased bacterial burdens that not only result in a negative physical impact (odour, exudates, pain, and infection) on patients, impairing their quality of life, but they also increase treatment costs. A systematic review of the effectiveness of that the silver-releasing dressing in the management of infected chronic wounds can help enhance control of wound bed infection and inflammation, tissue management, moisture balance, and protect wound edge. However, few studies have examined the effects on people with MFW. Hypothses In this study that the hypothesized that cancer patients in the ionic silver dressing group will perception higher quality of life compared to patients in the control group who receive non-ionic silver dressing. In addition, we hypothesized that cancer patients who also receive ionic silver dressing will have lower level of symptom distress at end of study compared to patients in the control group receive non-ionic silver dressing care.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Head and Neck Neoplasms | Head and Neck Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Ulcer | — | UNRESOLVED | — |
| Wounds | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| silver-releasing dressings | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- silver-releasing dressings
- description
- Silver, in its common ionic (active) form (Ag+), is particularly attractive as an antibacterial agent because it can be readily incorporated into dressing materials. Silver-dressing are wound products designed to control infection and provide a wound environment conducive to management exudates, pain, and malodour.
- interventionNames
- Other: silver-releasing dressings
Primary outcomes (1)
- measure
- The data are collected using questionnaires completed by the subjects themselves.In this study , the primary outcome is health-related quality of life (HRQOL)
- timeFrame
- Each group was followed up for two week
Secondary outcomes (1)
- measure
- Also, the Secondary outcome measure using the modified Schulz Malignant Wound Assessment Tool (mSMWAT)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * (1.)Had a first time diagnosis of cancer of the breast or head and neck with MFW; * (2)Are at least more than 18 years of age or older, in order to focus the study on an adult population * (3)Present at malignant fungating wound more than one month old; * (4)Are able to speak and understand Chinese, in order to understand the consent form and the intervention and complete the study questionnaires Exclusion Criteria: * (1) patients conscious unclear; * (2) Had seriously medical or psychology, such as hemodialysis; * (3) Had other comorbidity may interfere with intervention ion Criteria:
References
Publications (0)
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