Clinical trial · Interventional
CyberKnife for Unresectable Renal Tumors
CyberKnife Stereotactic Radiation for Unresectable Renal Tumors/PhaseI Study
NCT00807339CI-TRIAL-00026533completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a dose escalation study using the CyberKnife radiotherapy device for small surgical or medically untreatable renal tumors. Patients with renal tumors 5cms or less in diameter will be accrued onto this study. The ability of CyberKnife to ablate these renal tumors and maintain renal function with dose escalation will be assessed.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Cancer | Kidney Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CyberKnife Robotic Radiosurgery System | Device | — | UNRESOLVED |
| Stereotactic radiation | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- 1
- description
- Phase I dose escalation
- interventionNames
- Radiation: Stereotactic radiation
- Device: CyberKnife Robotic Radiosurgery System
Primary outcomes (1)
- measure
- To determine the maximum tolerated dose of CyberKnife radiation
- timeFrame
- 2 years
Secondary outcomes (1)
- measure
- To evaluate local control, overall survival and late toxicity including preservation of renal function
- timeFrame
- 2 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 95 Years
Show eligibility criteria text
Inclusion Criteria: * Tumor size 5 cm or less * Radiographic evidence of malignancy or Histologically verified primary renal malignancy. * If the kidney biopsy is inconclusive but the radiologist determines that the tumor based on the CT/MRI is highly suspicious for cancer, you may participate * Patients with highly suspicious lesions on CT or MRI * One -three gold fiducials placed in or around tumor * Contradiction or patient refusal to partial or complete nephrectomy * Age 18 or greater * KPS score 70 or greater Exclusion Criteria: * Irreversible coagulopathies that preclude fiducial placement
References
Publications (0)
Data not yet available
No reference posted for this study.