Clinical trial · Observational
Change in Penile Length Following Bilateral Nerve-Sparing Radical Prostatectomy
Assessing the Change in Penile Length Following Bilateral Nerve-Sparing Radical Prostatectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Some men complain of changes in the shape or dimensions of their penis after undergoing radical prostatectomy (removal of the prostate) for prostate cancer. Changes in penile dimensions include shortening or decreased girth. Changes in shape include a curvature or bending of the penis, and/or the appearance of indentation. These changes may be associated with formation of scar tissue involving the covering of the erection chambers, known as "plaque". The appearance of indurated plaque and a resultant curvature or indentation is a well described medical condition known as "Peyronie's Disease" and may occur in men who did or did not undergo radical prostatectomy. The purpose of this study is to evaluate these changes in penile shape and dimensions.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Penile Exam, Peyronie's Plaque and Erectile function assessment | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- open, laparoscopic, or robotic-assisted lap
- description
- Patients will also be assessed for penile length and the presence of Peyronie's Disease at these specified times.
- interventionNames
- Behavioral: Penile Exam, Peyronie's Plaque and Erectile function assessment
Primary outcomes (2)
- measure
- Assess the impact of radical retropubic prostatectomy on penile dimensions.
- timeFrame
- conclusion of the study
- measure
- Assess the impact of radical retropubic prostatectomy on the development of Peyronie's Disease.
- timeFrame
- conclusion of the study
Secondary outcomes (1)
- measure
- Assess the association between penile length change and erectile function.
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Males, age 21 years or older (no maximum age limit) * Ability and willingness to give informed consent * Clinically localized prostate cancer * Open, laparoscopic or robotic-assisted radical prostatectomy * Must be sexually active (penetrative or non-penetrative sexual encounters, either with a partner or self-stimulation) Exclusion Criteria: * Preoperative / Postoperative pelvic radiation therapy * Preoperative / Postoperative hormonal treatment * Preoperative Peyronie's disease * Preoperative presence of a penile implant
References
Publications (0)
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