Clinical trial · Observational
Quality of Life After Esophagectomy for Cancer
Role of Pyloric Drainage in Reflux Symptoms After Esophagectomy for Cancer
NCT00798746CI-TRIAL-00007623completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the current study is to assess the role of pyloric drainage procedure on altering the reflux effect on the quality of life in patients who underwent esophagectomy. Researchers hypothesize that the patients who underwent minimally invasive esophagectomies without pyloric drainage experience less reflux symptoms and therefore have a better quality of life.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Telephone Questionnaire | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Pyloric Drainage Procedure
- description
- Esophagectomy with pyloric drainage procedure
- interventionNames
- Behavioral: Telephone Questionnaire
- label
- No Pyloric Drainage Procedure
- description
- Esophagectomy without pyloric drainage procedure
- interventionNames
- Behavioral: Telephone Questionnaire
Primary outcomes (1)
- measure
- Reflux Symptoms: Open Esophagectomy versus Minimally Invasive
- timeFrame
- Survey response collected at single point in time.
- description
- Comparison of reflux symptoms in patients who underwent open esophagectomies with pyloric drainage and those who received minimally invasive esophagectomies without pyloric drainage. The survey consisted of ten questions regarding symptoms associated with reflux using Gastrointestinal Symptoms Rating Scale (GSRS). Responses to degree of reflux distress rated on a six-point scale for questions with "0" indicating no heartburn symptoms and "5" indicating most symptoms experienced.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. patients who are 18 years-old or older 2. Patients who received esophagectomy indicated for primary esophageal cancer, either adenocarcinoma or squamous cell carcinoma 3. Patients who received minimally invasive or transthoracic or transhiatal or three-field esophagectomy at MDACC during or after 2004 4. Patients who are English-speaking and of any ethnicity 5. Patients with prior cancers, any clinical stage of esophageal carcinoma, any performance status (as rated by American Society of Anesthesiologist Risk Scale), received or did not receive preoperative treatment, had level of anastomosis in either neck or chest Exclusion Criteria: 1\) Patients who received esophagectomies indicated for emergency, salvage or redo
References
Publications (0)
Data not yet available
No reference posted for this study.