Clinical trial · Interventional
Preoperative Biliary Drainage for Resectable Hilar Cholangiocarcinoma
Effect of Preoperative Biliary Drainage on Postoperative Complications in Resectable Patients With Hilar Cholangiocarcinoma(Klatskin Tumor)
NCT00797121CI-TRIAL-00001806unknownPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is to investigate whether preoperative biliary drainage can reduce the postoperative morbidity in patients with hilar cholangiocarcinoma.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cholangiocarcinoma | Cholangiocarcinoma | ONTOLOGY_EXACT | 0.98 |
| Drainage | — | UNRESOLVED | — |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Preoperative biliary drainage | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Preoperative biliary drainage
- interventionNames
- Procedure: Preoperative biliary drainage
- type
- NO_INTERVENTION
- label
- Controlled group
Primary outcomes (1)
- measure
- Incidence of postoperative complication
- timeFrame
- 30 days after operation
Secondary outcomes (3)
- measure
- Postoperative mortality
- timeFrame
- 30 days after operation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients newly diagnosed * Resectable patients after imaging assessment and evaluation of general condition of the patient * TB\>85μmol/L * WBC account more than 1.5×109/L, PLT account more than 100×109/L and HB account more than 100g/L * No serious disease in heart, lung and kidney * Written informed consent Exclusion Criteria: * Unresectable patients. * Patients have received biliary drainage procedure such as PTBD before admission * Complicated with chronic hepatitis * Myocardia infarction record within six months * Women in pregnancy * Serious disease in heart, lung or kidney
References
Publications (2)
- BACKGROUNDJarnagin WR, Fong Y, DeMatteo RP, Gonen M, Burke EC, Bodniewicz BS J, Youssef BA M, Klimstra D, Blumgart LH. Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma. Ann Surg. 2001 Oct;234(4):507-17; discussion 517-9. doi: 10.1097/00000658-200110000-00010. PMID 11573044
- BACKGROUNDNimura Y, Kamiya J, Kondo S, Nagino M, Uesaka K, Oda K, Sano T, Yamamoto H, Hayakawa N. Aggressive preoperative management and extended surgery for hilar cholangiocarcinoma: Nagoya experience. J Hepatobiliary Pancreat Surg. 2000;7(2):155-62. doi: 10.1007/s005340050170. PMID 10982608