Flaxseed in Preventing Breast Cancer in Premenopausal Women at Risk of Developing Breast Cancer

* Patients enrolled in must meet ≥ 1 of the following criteria:

  * History of unilateral or bilateral atypical ductal hyperplasia with or without family history
  * History of atypical lobular hyperplasia or lobular carcinoma in situ with or without family history
  * History of ductal carcinoma in situ
  * Prior stage I breast cancer allowed provided it was adequately treated and therapy was completed ≥ 1 year ago
  * Lifetime risk for developing breast cancer \> 20% (based on Gail or Claus model)
  * No abnormal mammogram requiring short-term follow-up within the past 6 months
  * No severe atypia or carcinoma cells on RPRNA

PATIENT CHARACTERISTICS:

* Premenopausal
* ECOG performance status 0-1
* Patients enrolled must meet the following criteria:

  * No peri- or postmenopausal status as determined by estradiol levels \< 20 ng/dL and FSH levels \> 45 ng/dL
  * No thrombocytopenia (defined as platelet count \< 50,000/mm\^3)
  * Creatinine ≤ 1.5 mg/dL
  * Not pregnant or nursing
  * Fertile patients must use effective contraception consistently
  * No other prior malignancy allowed except for the following:

    * Basal cell or squamous cell carcinoma
    * In situ cervical cancer
  * No history of any of the following conditions within the past 5 years:

    * Crohn disease
    * Ulcerative colitis
    * Inflammatory bowel disease
    * Irritable bowel syndrome
    * Celiac sprue
    * Malabsorption syndrome
    * Diverticulitis
    * Diverticulosis
  * No allergy to flaxseed, other seeds or nuts, or wheat

PRIOR CONCURRENT THERAPY:

* Patients enrolled in part 1 must meet the following criteria:

  * No prior breast implants or tram-flap reconstruction

    * Breast reduction allowed
  * No prior neoadjuvant chemotherapy or other chemotherapy within the past year
  * No prior neoadjuvant hormonal therapy
  * No prior whole radiation to the contralateral breast undergoing random periareolar fine needle aspiration (RPFNA)
  * No concurrent coumadin or other chronic anticoagulants (even if they are held for surgery)
* Patients enrolled in part 2 must meet the following criteria:

  * More than 1 year since prior chemotherapy and adjuvant hormonal therapy for breast cancer

    * No concurrent chemotherapy for breast cancer
  * At least 1 month since prior and no concurrent treatment with corticosteroid
  * At least 2 weeks since prior and no concurrent use of antibiotics
  * At least 2 weeks
  * No history of chest wall irradiation
  * No presence of breast implants
  * No prior or concurrent tamoxifen within the past 90 days
  * No chronic/concurrent medications that inhibit platelet function, including any of the following:

    * Aspirin
    * Non-steroidal anti-inflammatory drugs (i.e., Aleve®, Motrin®, ibuprofen)
    * Coumadin
    * Heparin
    * Low molecular weight heparin
    * Anti-platelet agents

      * No prior short-term use of platelet inhibitors ≥ 7 days prior to RPFNA
  * No concurrent ingestion of the following:

    * Pumpkin seeds
    * Sesame seeds
    * Fish oil supplements
  * At least 30 days since prior and no concurrent flaxseed supplements, fish oil, or flaxseed oil
  * No concurrent treatment for another malignancy