Clinical trial · Observational
Characterization of At-risk Population for Pre-sacral Tumor in CURRARINO Syndrome
Characterization of At-risk Population and Prognosis Factors for SACRO-coccygeal Teratoma in CURRARINO Syndrome. A Clinical, Molecular and Pathological Study.
NCT00780117CI-TRIAL-00106889CurrarinocompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Contribute to support hypothesis of relationships between genes involve in oncogenesis and those involve in embryological development.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| CURRARINO Syndrome | — | UNRESOLVED | — |
| Presacral Mass | — | UNRESOLVED | — |
| Sacrococcygeal Teratoma | Sacrococcygeal Teratoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Annual lumbar-sacral MRI is performed
- timeFrame
- one year
Secondary outcomes (2)
- measure
- Pathological tumoral tissue analysis after surgical removal
- timeFrame
- 3 years
- measure
- Annual serum alpha-foeto protein level monitoring
- timeFrame
- one year
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * At least 1 out of the 4 major signs of CURRARINO syndrome: 1. Sacral agenesis 2. Hindgut malformation or chronic constipation 3. Presacral tumor and/or 4. TETHECORD syndrome and/or lipoma of the filum or the conus * Anomaly genotyping HLXB9 without clinical expression Exclusion Criteria: \- Opposition to sign informed consent agreement
References
Publications (0)
Data not yet available
No reference posted for this study.