Clinical trial · Interventional
A Study of a Home-based Exercise Intervention for Patients With Acute Myeloid Leukaemia (AML)
A Pilot Study of a Home-based Exercise Intervention for Patients With AML
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Fatigue is the most common and disabling symptom in acute myeloid leukaemia (AML). Studies in other cancer patients with fatigue have shown that exercise improves both fatigue and quality of life (QOL), but there are no such studies in AML. The investigators want to conduct a pilot study of a home-based exercise program to see if this type of exercise program is feasible for AML patients, reduces fatigue, and improves QOL. What the investigators learn from this study will be essential to designing a larger, definitive randomized trial of exercise in patients with AML.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Myeloid Leukemia | Acute Myeloid Leukemia | CURATED_BROADER | 0.80 |
| Exercise | — | UNRESOLVED | — |
| Fatigue | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Home-based exercise program | Behavioral | — | UNRESOLVED |
| Wait list | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Exercise
- description
- This group will undergo a 12-week home-based exercise intervention with follow-up fitness assessments.
- interventionNames
- Behavioral: Home-based exercise program
- type
- OTHER
- label
- Wait list control
- description
- This group will go on a 12-week wait list, during which time they will be asked not to change their exercise habits. After 12 weeks, this group will participate in the exercise intervention.
- interventionNames
- Behavioral: Wait list
Primary outcomes (1)
- measure
- Quality of life (fatigue, global health)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 79 Years
Show eligibility criteria text
Inclusion Criteria: * Completion of induction and consolidation chemotherapy * AML with histologically confirmed complete remission * Fluency in English (or availability of bilingual caregiver and fluency in language for which validated translations of the FACT-Fatigue exist) * Potential participants must also be screened with the Physical Activity Readiness Questionnaire (PAR-Q \& PAR-MedX) and receive physician approval to participate in an exercise program Exclusion Criteria: * Another active malignancy * Life expectancy \< 3 months * Severe or unstable cardiorespiratory disease * Bone marrow transplant candidates
References
Publications (0)
Data not yet available