Clinical trial · Interventional
Efficacy and Safety Study of ZOMETA® in Treatment of High-level NTX Non Small Cell Lung Cancer With Bone Metastasis
NCT00762346CI-TRIAL-00012915completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A multicenter prospective study to assess the efficacy and safety of ZOMETA® in treatment of high-level NTX non small cell lung cancer with bone metastasis.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Metastases | — | UNRESOLVED | — |
| High NTX Level | — | UNRESOLVED | — |
| Non Small Cell Lung Cancer | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| zometa | Drug | Zoledronic Acid | ALIAS |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- 1
- interventionNames
- Drug: zometa
Primary outcomes (1)
- measure
- Skeleton-related event
- timeFrame
- 2 years
Secondary outcomes (1)
- measure
- OS
- timeFrame
- 2 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \> 18 * Histologically confirmed non-small cell cancer * One bone metastasis at least confirmed by image(X ray, CT or others) * NTX \> 50nM BCE/mM creatinine * Life expectancy \> 6 M * ECOG \<= 2 * Signed ICF Exclusion Criteria: * Women who are pregnant or in lactation * Patients with hyperostosis with brain metastasis(exception of those without symptom or with Metastasis Lesions under controlled * Previous or current treatment with any other bisphosphonates, bone- protecting, cytotoxic or targeted therapy * Severe co-morbidity of any type that may interfere with assessment of the patient for the study -
References
Publications (0)
Data not yet available
No reference posted for this study.