Clinical trial · Observational
Study of Genes and Environment in Patients With Breast Cancer in the East Anglia Region of the United Kingdom
A Population Based Study of Genetic Predisposition and Gene-Environment Interactions in Breast Cancer in East Anglia
NCT00757211CI-TRIAL-00011870unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This study is looking at genetic susceptibility to cancer and interactions between genes and the environment in patients with breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laboratory biomarker analysis | Other | — | UNRESOLVED |
| polymorphism analysis | Genetic | — | UNRESOLVED |
| questionnaire administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (5)
- measure
- Acquisition of epidemiological information and biological material
- measure
- Investigation of whether polymorphisms in putative cancer predisposition genes are associated with an increased risk of breast cancer
- measure
- Proportion of breast cancer incidence attributable to mutations in such genes
- measure
- Examination of the interactions between genetic and nongenetic risk factors
- measure
- Evaluation of the relationship between pathological and clinical characteristics of breast cancers and germline genotype
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Diagnosis of breast cancer within the past 5 years * Identified through the East Anglian Cancer Registry in the East Anglia region of the United Kingdom * Hormone receptor status not specified PATIENT CHARACTERISTICS: * Menopausal status not specified * Identified by the patient's general practitioner as fit to contact for this study * No serious mental illness or retardation PRIOR CONCURRENT THERAPY: * Not specified
References
Publications (0)
Data not yet available
No reference posted for this study.