Clinical trial · Interventional
Pegfilgrastim for Stem Cell Mobilization in Children (Meg-5)
Haematopoietic Progenitor Cell Mobilization in Children With Malignancies: Evaluation of Pegfilgrastim at 200µg/kg After Chemotherapy
NCT00751894CI-TRIAL-00004304MEG-5unknownPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Hypothesis : pegfilgrastim at 200 µg/kg between 12 and 18 days after previous chemotherapy provides an efficient stem cell mobilization in children with malignancies Design: phase 2 study. Judgment criterion: percentage of children achieving at least 5x10e6 CD34 cells with a standard apheresis (less than 3 blood volume processed
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Malignancies | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pegfilgrastim (Neulasta, Amgen) | Drug | Pegfilgrastim | ALIAS |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- percentage of children achieving at least 5x10e6 CD34 cells with a standard apheresis (less than 3 blood volume processed)
- timeFrame
- less than 3 blood volume processed
Secondary outcomes (1)
- measure
- Side effects Number of apheresis required to achieved a graft of at least 5x10e6 CD34 cells
- timeFrame
- at least 5*10e6CD34cells
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 0 to 18 years * solid malignancy * Lansky score \>70% * 12 to 18 days since the beginning of the last chemotherapy cycle * no administration of any hematopoietic growth factor in the previous 8 days Exclusion Criteria: * clinical or biological conditions precluding the mobilization or collection procedure
References
Publications (0)
Data not yet available
No reference posted for this study.