Clinical trial · Interventional
Colonography Versus Colonoscopy in High Risk Patient
Acceptability and Effectiveness of Colonography Compared to Colonoscopy for the Detection of Advanced Adenomas in Patients at High Risk for Colorectal Cancer
NCT00748449CI-TRIAL-00104923COLO-TDMterminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): No more inclusions
Summary
Brief summary (as posted)
to evaluate the acceptability of CT-colonography compared to colonoscopy for the detection of advanced adenomas in subpopulations at high risk of colorectal.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Colonoscopy | Procedure | — | UNRESOLVED |
| CT-colonography | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- 1
- description
- CT Colonography
- interventionNames
- Procedure: CT-colonography
- type
- ACTIVE_COMPARATOR
- label
- 2
- description
- Colonoscopy
- interventionNames
- Procedure: Colonoscopy
Primary outcomes (1)
- measure
- Percentage of patients who refuse to undergo an examination
- timeFrame
- 36 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: Surveillance of patients with a personal history of advanced adenoma or CRC: * Informed consent obtained * Age ≥ 18 and ≤ 80 years old * History of advanced adenomatous polyps * Or history of non metastatic CRC with curative surgery and without other treatment more than 2 years before enrollment. * Previous medical examination Screening of patients with a Family history of CRC at high risk: * Informed consent obtained * Age ≥ 18 and ≤ 80 years old * First degree family history of colorectal cancer diagnosed \<60yrs during the five previous years-Previous medical examination Exclusion Criteria: Personal histories * Age \< 18 or \>80 years old * history of non adenomatous polyps * history of Metastatic CRC * familial adenomatous polyposis, Peutz-Jeghers syndrome, hereditary non polyposis colorectal cancer (HNPCC), juvenile polyposis syndrome * Familial history of familial adenomatous polyposis * Personal history of subtotal colectomy (but not of hemicolectomy, to confer to inclusion criteria) * Colonoscopy with a polyps resection dated more than 5 years and less than 2 years prior to enrollment. * Enrollment in another protocol * no health insurance affiliation Family histories * Age \< 18 or \>80 years old * Patients with one or several family histories of first degree colorectal cancer occured to unknown age or diagnosed after 60 years old. * Eligible patients having already undergone colonoscopy screening * no health insurance affiliation
References
Publications (0)
Data not yet available
No reference posted for this study.