Clinical trial · Interventional
Photodynamic Therapy Using Aminolevulinic Acid in Treating Patients With Skin Cancer
Investigation of the Effectiveness of Non-Coherent Blue Light in Intralesional Photodynamic of Basal Cell Carcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Photodynamic therapy uses a drug that becomes active when it is exposed to a certain kind of light. When the drug is active, tumor cells are killed. This may be an effective treatment against skin cancer. PURPOSE: This phase II trial is studying the side effects of photodynamic therapy using aminolevulinic acid and to see how well it works in treating patients with skin cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Non-melanomatous Skin Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| aminolevulinic acid hydrochloride | Drug | Aminolevulinic Acid | ALIAS |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Safety
- measure
- Efficacy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 30 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Biopsy-proven basal cell carcinoma on the trunk or extremities * Tumor size ≤ 2 cm in diameter PATIENT CHARACTERISTICS: * Willing and able to comply with all follow-up requirements * Mentally competent * No active, localized, or systemic infections * Not immunocompromised * No coagulation disorder * No photosensitivity or allergy to sunlight * Not pregnant or nursing * No history of keloid formation * No history of cutaneous photosensitization, porphyria, hypersensitivity to porphyrins, or photodermatosis PRIOR CONCURRENT THERAPY: * No prior gold therapy * No prior radiotherapy to the trunk and extremities * More than 24 months since prior oral retinoids (e.g., isotretinoin or acitretin) or photosensitizing drugs (e.g., Declomycin®) * More than 1 year since prior collagen or other injections, Botox® injections, chemical peels, dermabrasion, or resurfacing procedures * More than 1 month since prior topical retinoid therapy * No concurrent aspirin or antioxidants * No concurrent anticoagulation medications
References
Publications (0)
Data not yet available