Clinical trial · Interventional
Cardiopulmonary Exercise Testing and Preoperative Risk Stratification
A Randomised Controlled Trial of the Utility of Cardiopulmonary Exercise (CPX) Testing for Preoperative Risk Stratification to Guide Perioperative Care and Thereby Reduce Postoperative Morbidity
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators would like to evaluate the use of cardiopulmonary exercise tests (CPX) in guiding the care pathway of patients undergoing colorectal operations. In the intervention group care will be guided by CPX results and in the control group care will be guided by the doctors assessment. The investigators would like to assess the impact of this on patient outcome, patient satisfaction and resource usage.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anaesthesia | — | UNRESOLVED | — |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Critical Illness | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Perioperative care pathway guided by CPX results | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- A
- description
- Control - Standard Perioperative Pathway, clinician decides post-operative care environment (usual care)
- interventionNames
- Other: Perioperative care pathway guided by CPX results
- type
- EXPERIMENTAL
- label
- B
- description
- Intervention - Perioperative care pathway guided by CPX Results i.e.anaerobic threshold \& ventilatory equivalents
- interventionNames
- Other: Perioperative care pathway guided by CPX results
Primary outcomes (1)
- measure
- Postoperative morbidity (presence or absence of POMS defined morbidity)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Adults ≥ 18 years age 2. Males 3. Females 4. Listed for elective(non-emergency) colorectal surgery Exclusion Criteria: 1. Age \< 18 years age 2. Patient unwilling/unable to consent 3. Adults with learning disabilities or dementia 4. Prisoners 5. Any contraindication to cardiopulmonary exercise testing (as outlined by \*American Association of Anaesthesia: * Acute MI (3-5 days) * Unstable angina * Uncontrolled arrhythmias * Syncope * Acute endocarditis * Acute myocarditis * Acute pericarditis * Symptomatic severe aortic stenosis * Uncontrolled heart failure * Acute pulmonary embolism or infarction * Thrombosis of lower extremities * Dissecting aneurysm * Uncontrolled asthma * Pulmonary oedema * Room air desaturation at rest \<85% * Respiratory failure * Acute non-cardiopulmonary disorder that may affect exercise performance or be aggravated by exercise Mental impairment leading to inability to co-operate 6. Patients already enrolled in an interventional study 7. Previous CPX test result recorded in the medical notes
References
Publications (0)
Data not yet available