Clinical trial · Observational
Pharmacogenetic Determinants Of Treatment Response In Children
NCT00730678CI-TRIAL-00109837recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic substrates. To investigate the nature of heritability and the genetic basis of pharmacogenetic traits by studying family members of individuals with specific genotypes.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| All Malignancies | — | UNRESOLVED | — |
| Children Being Treated for Catastrophic Illness | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- All Participants
- description
- All participants enrolled on this study will have blood drawn for genetic testing.
Primary outcomes (1)
- measure
- To investigate whether genetic polymorphisms in genes encoding proteins involved in the metabolism or effects of drugs or environmental agents influence the disposition or effects of these xenobiotic substrates.
- timeFrame
- 28 years
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Any patients under evaluation/treatment at St. Jude Children's Research Hospital (SJCRH) * Parents or family members of St. Jude patients * Non patient volunteers * All study subjects must provide informed consent for participation * Assent/Consent of the patient (parent) must be provided prior to attempts made by investigators to enroll a family member of a SJCRH patient Exclusion Criteria:
References
Publications (0)
Data not yet available
No reference posted for this study.