Clinical trial · Interventional
A Yoga and Wellness Program for Breast Cancer Survivors With Persistent Fatigue
Iyengar Yoga for Breast Cancer Survivors With Persistent Fatigue
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized controlled trial will compare the effectiveness of an Iyengar Yoga intervention to a Wellness Seminar health education lecture series, for improvements in energy, mood and biological functioning in breast cancer survivors with persistent, post-treatment fatigue. It is anticipated that the Iyengar Yoga intervention will be feasible and acceptable to breast cancer survivors with minimal side effects and that the Yoga intervention will be effective in improving fatigue and physical performance.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Fatigue | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Iyengar Yoga | Other | — | UNRESOLVED |
| Wellness Seminar Series | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- 1
- description
- Yoga
- interventionNames
- Other: Iyengar Yoga
- type
- ACTIVE_COMPARATOR
- label
- 2
- description
- A Wellness Seminar series
- interventionNames
- Other: Wellness Seminar Series
Primary outcomes (1)
- measure
- Fatigue
- timeFrame
- Measured at baseline, after the 12 week intervention and at 3 months post-intervention
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 40 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosed with early, resectable breast cancer (Stage I or II) * Completed treatment with surgery, radiation, and/or chemotherapy between 6 months and 5 years previously * No other cancer in last 5 years, including breast cancer recurrence * Postmenopausal women * Age 40 - 65 * Reporting persistent cancer-related fatigue Exclusion Criteria: * Evidence that fatigue is directly related to a medical or psychiatric disorder (e.g., untreated hypothyroidism, diabetes, anemia (defined as hematocrit \< 24), chronic fatigue syndrome, current major depression, insomnia, sleep apnea, restless leg syndrome) * Evidence that fatigue is related to other non-cancer related factors (e.g., shift work, recent change in activity or schedule) * Physical problems or conditions that could make yoga unsafe (e.g., serious neck injuries, unstable joints; also severe cachexia, dizziness, bone pain, severe nausea, etc) * Regular use of medications and/or behavioral therapies that would confound evaluation of IY, including regular participation in yoga classes * Presence of medical conditions that involve the immune system and would confound immune evaluation (e.g., autoimmune disorder, inflammatory disease) * Use of medications that might confound immune evaluation (e.g., regular use of corticosteroids, narcotics, opiates) * Unable to commit to intervention schedule * Body mass index greater than 30 kg/m2 * Regular tobacco (defined as daily or near daily) or alcohol use (defined as \> 2 drinks/day)
References
Publications (1)
- BACKGROUNDBower JE, Woolery A, Sternlieb B, Garet D. Yoga for cancer patients and survivors. Cancer Control. 2005 Jul;12(3):165-71. doi: 10.1177/107327480501200304. PMID 16062164