Clinical trial · Interventional
Radiation Therapy in Treating Patients With Metastatic Spinal Cord Compression
SCORAD: A Randomised Feasibility Study of Single Fraction Radiotherapy Compared to Multi-fraction Radiotherapy in Patients With Metastatic Spinal Cord Compression
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. It is not yet known which radiation therapy regimen is more effective in treating metastatic spinal cord compression. PURPOSE: This randomized clinical trial is comparing two radiation therapy regimens to see how well they work in treating patients with metastatic spinal cord compression.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Spinal Cord Compression | — | UNRESOLVED | — |
| Unspecified Adult Solid Tumor, Protocol Specific | Adult Solid Neoplasm | ALIAS | 0.85 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| radiation therapy | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Arm I (multi-fraction radiotherapy)
- description
- Patients undergo 5 fractions of 20 Gy external-beam radiotherapy.
- interventionNames
- Radiation: radiation therapy
- type
- EXPERIMENTAL
- label
- Arm II (single-fraction radiotherapy)
- description
- Patients undergo 1 fraction of 8 Gy external beam radiotherapy.
- interventionNames
- Radiation: radiation therapy
Primary outcomes (1)
- measure
- Patient accrual per center over a 12-month period
Secondary outcomes (9)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Histologically or cytologically confirmed malignant disease * Proven diagnosis of metastatic spinal cord compression on MRI or CT scan * Single site of compression OR multiple sites that can be treated within a single radiation treatment field * No patient for whom surgery or chemotherapy treatment is more appropriate * No multiple myeloma as primary cancer PATIENT CHARACTERISTICS: * Life expectancy \> 1 month * Not pregnant * Willing and able to complete assessment forms * Able to give informed consent PRIOR CONCURRENT THERAPY: * See Disease Characteristics
References
Publications (0)
Data not yet available