Clinical trial · Observational
Incidence and Patterns of Nausea/Vomiting With Combined Chemotherapy and Radiation
A Prospective Study to Evaluate the Incidence and Patterns of Nausea and Vomiting in Patients Receiving Combined Chemotherapy and Radiation
NCT00716157CI-TRIAL-00016267completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Questionnaire study to observe the incidence and pattern or nausea and vomiting in patients receiving combined chemotherapy and radiation. 83% of patients experience radiation therapy-induced vomiting; significant nausea and vomiting could develop with concurrent chemotherapy despite standard anti-nauseous medication prophylaxis.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer of the Esophagus | Malignant Esophageal Neoplasm | ALIAS | 0.90 |
| Cancer of the Head and Neck | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Cancer of the Lung | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Gastro-esophageal Junction Cancer | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- Observation
- description
- Adult patients receiving both radiation therapy and chemotherapy
Primary outcomes (1)
- measure
- Assess incidence and patterns of nausea and vomiting in patients undergoing concurrent chemotherapy and radiation
- timeFrame
- week of treatment
Secondary outcomes (2)
- measure
- Assess the impact of nausea and vomiting on the patients' daily functioning
- timeFrame
- week of treatment
- measure
- Study the incidence of mucositis and esophagitis
- timeFrame
- week of treatment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Concurrent radiation and chemotherapy treatment * Aerodigestive malignancy Exclusion Criteria: * Other causes of vomiting (i.e.gastrointestinal obstruction...)
References
Publications (0)
Data not yet available
No reference posted for this study.