Clinical trial · Interventional
Evaluation of Pegfilgrastim for Stem Cell Mobilization in Children
Hematopoietic Progenitor Cell Mobilization in Children With Malignancies: Evaluation of Pegfilgrastim at 300µg/kg in Hematological Steady State
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Recruiting or enrolling participants has halted and will not resume
Summary
Brief summary (as posted)
Hypothesis: pegfilgrastim at 300 µg/kg in hematological steady state provides an efficient stem cell mobilization in children with malignancies Design: phase 2 study. Judgment criterion: percentage of children achieving at least 5x10e6 CD34 cells with a standard apheresis (less than 2 blood volume processed)
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Malignancies | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pegfilgrastim (drug) | Drug | Pegfilgrastim | ALIAS |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- percentage of children achieving at least 5x10e6 CD34 cells with a standard apheresis (less than 2 blood volume processed)
Secondary outcomes (1)
- measure
- Side effects Number of apheresis required to achieved a graft of at least 5x10e6 CD34 cells
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 0 to 18 years * solid malignancy * Lansky score \>70% * more than 17 days since the beginning of the last chemotherapy cycle * absolute neutrophil count (ANC) greater than 1×109/l * no administration of any hematopoietic growth factor in the previous 8 days Exclusion Criteria: * clinical or biological conditions precluding the mobilization or collection procedure
References
Publications (0)
Data not yet available