Clinical trial · Observational
Long-term Active Surveillance Study for Oral Contraceptives (LASS)
NCT00676065CI-TRIAL-00016098completedResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this study is to characterize and compare the risks of long-term use of oral contraceptives containing drospirenone and of other established oral contraceptives.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Arterial Thromboembolism | — | UNRESOLVED | — |
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Venous Thromboembolism | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (3)
- label
- 1
- description
- Women who take oral contraceptives containing drospirenone
- label
- 2
- description
- Women who take oral contraceptives containing levonorgestrel
- label
- 3
- description
- Women who take oral contraceptives containing other progestogens
Primary outcomes (3)
- measure
- Arterial Thromboembolism
- timeFrame
- Within 10 years
- description
- Arterial thromboembolism associated with the use of oral contraceptives containing drospirenone or levonorgestrel or other progestogens.
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * Women who are prescribed an oral contraceptive and who are new users (first-ever users, switchers or restarters) of the formulation Exclusion Criteria: * Women who do not consent to participate in the study
References
Publications (1)
- DERIVEDDinger J, Mohner S, Heinemann K. Cardiovascular risks associated with the use of drospirenone-containing combined oral contraceptives. Contraception. 2016 May;93(5):378-85. doi: 10.1016/j.contraception.2016.01.012. Epub 2016 Jan 26. PMID 26825258