Clinical trial · Interventional
Randomized Controlled Trial Comparing Co2 vs. Air in Colonoscopy in Sedated Patients
NCT00660296CI-TRIAL-00001408unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
CO2 insufflation instead of air for colonic distension in colonoscopy is considered to reduce pain after and during colonoscopy. There is limited data, that Co2 is similar effective in sedated patients. Furthermore it had not been investigated if patient's compliance for participating in cancer screening could be improved by using Co2. The aim of the study is to assess postoperative pain and satisfaction after colonoscopy by comparing C02 with air.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pain, Satisfaction | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Air insufflation use in colonoscopy | Other | — | UNRESOLVED |
| CO2 use in colonoscopy | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- 2
- description
- Air insufflation in colonoscopy
- interventionNames
- Other: Air insufflation use in colonoscopy
- type
- OTHER
- label
- 1
- description
- CO2 insufflation in colonoscopy
- interventionNames
- Other: CO2 use in colonoscopy
Primary outcomes (1)
- measure
- Pain after Colonoscopy measured by 100mm visual analogue scale.
- timeFrame
- 15 and 30 minutes and 6 h and 12 h after colonoscopy
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * All patients, who are assigned to an outdoor ambulance for elective colonoscopy in sedation * Between 18 and 90 years Exclusion Criteria: * COPD * Dementia
References
Publications (1)
- RESULTBretthauer M, Lynge AB, Thiis-Evensen E, Hoff G, Fausa O, Aabakken L. Carbon dioxide insufflation in colonoscopy: safe and effective in sedated patients. Endoscopy. 2005 Aug;37(8):706-9. doi: 10.1055/s-2005-870154. PMID 16032487